Old whooping cough vaccine protected better than new
An older version of the whooping cough vaccine offered
better protection against the disease than the current version does, a new
study from Australia suggests.
Children who received the older version of the vaccine
were less likely to catch the disease before age 12, compared with those who
received the newer version of the vaccine, or a combination of the two
vaccines, the study found.
The study followed the children during a three-year
whooping cough epidemic, which is still taking place in Australia, and nine
years before the epidemic.
The work agrees with previous studies showing the
protection offered by the newer whooping cough vaccine, called the acellular
pertussis vaccine, wanes after a few years. (Whooping cough is also known as
pertussis.)
The acellular pertussis vaccine was introduced in the
United States in 1997, and Australia in 1999, after concerns that the previous
vaccine, called the whole cell pertussis vaccine, caused unwanted side effects
in some. These side effects included fever and swelling at the injection site.
The older version was less purified, but its protection was thought to last for
most of a person's life.
The challenge will be to develop a whooping cough vaccine
that offers long-lasting protection from the very first dose, without adverse
effects, the researchers of the new study said.
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